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2025-08-30 22:06:21

Palmitoylethanolamide (PEA)

What is PEA and How Can It Help with Pain and Inflammation?

If you’ve been living with ongoing pain or inflammation, you’ve probably tried many different ways to find relief. One option that’s gaining attention in the health world is Palmitoylethanolamide (PEA) — a naturally occurring compound that supports the body’s own ability to manage discomfort.

Let’s break down what PEA is, how it works, and why people are talking about it.


What is PEA?

PEA (Palmitoylethanolamide) is a fatty compound that our bodies produce in small amounts to help calm inflammation and protect our cells. It’s also found in certain foods like peanuts, soybeans, and egg yolks.

Researchers have been studying PEA for decades, and there’s growing evidence that it may help with a variety of pain-related conditions, especially those linked to chronic inflammation or nerve irritation.


⚡ How Does PEA Work?

Think of PEA as a natural body signal that tells overactive immune cells to calm down. When inflammation is triggered by arthritis, injury, or nerve irritation, the body sometimes keeps sending pain signals even when healing should have started.

PEA works by:

  • Regulating the activity of mast cells (cells that drive inflammation)

  • Supporting the body’s endocannabinoid system (the same system linked to stress, mood, and pain balance)

  • Helping restore a healthy pain response without being addictive or sedating


Potential Benefits of PEA

Studies suggest PEA may support people dealing with:

  • Joint pain and arthritis

  • Nerve pain (such as sciatica, carpal tunnel, or diabetic nerve pain)

  • Muscle soreness and recovery

  • Widespread pain conditions like fibromyalgia

Many people use PEA as a daily supplement to help reduce flare-ups and support long-term comfort.


✅ Why People Like PEA

  • Naturally produced by the body → gentle on the system

  • Non-addictive → unlike some pain medicines, it doesn’t cause dependence

  • Minimal side effects → generally well tolerated in clinical studies

  • Backed by research → over 60 years of investigation into its role in pain management

How is PEA Taken?

PEA is available as a capsule or powder. Doses vary depending on the product, but it’s usually taken once or twice daily. Because it works gradually, it may take a few weeks of regular use before you notice the full effect.

(Tip: Always follow the instructions on your supplement and check with a healthcare professional before starting anything new.)

Thinking About Trying PEA?

If pain and inflammation are impacting your daily life, PEA may be a natural option worth exploring. While it’s not a “magic cure,” it may provide real support alongside your usual treatments.

If you’d like to know more, speak with our pharmacist today for personalised advice.